安慰剂效应为什么有效?
字幕摘录
| 时间 | 英文 | 中文 |
|---|---|---|
| 0:02 | The stones are great and a magic power they have. | 石头是伟大的 和魔法的力量,他们拥有。 |
| 0:06 | Men that are sick fare to that stone and they wash that stone and with that water bathe away their sickness. | 生病的人去那块石头 洗了那块石头 水洗了他们的病 |
| 0:21 | The placebo effect has been known about for ages and always been considered hugely important in the history of medicine. | 安慰剂效应已久闻名于世,在医学史上始终被认为是极其重要的. |
| 0:27 | The great monument Stonehenge may actually have been a kind of placebo hospital, a place to which people came in order to receive faith cures. | 伟大的纪念碑巨石阵可能其实是一类安慰剂医院,人们为了获得信仰治疗而来的地方. |
| 0:37 | What they did we believe is to touch the stones and through them absorb as they believed some magically potent medicine. | 我们所相信的就是触摸石头,通过石头吸收 因为他们相信一些神奇的药。 |
| 0:46 | But it's only recently that science has begun to get to grips with what's actually going on when people respond to placebo treatments by reducing their sense of pain. | 但直到最近,科学才开始控制 当人们通过降低痛苦感来应对安慰剂治疗时, 实际发生的事情。 |
| 0:57 | The placebo effect involves the use of the endogenous opiates, our own internal painkillers, a drug rather like morphine which we release in order to control pain. | 安慰剂效应涉及使用内生阿片剂,即我们自己的内止痛药,是一种药物,类似于我们为了控制疼痛而释放的吗啡。 |
| 1:08 | What's always interested me though is the other question, the real mystery, not how they work, actually why placebos work. | 但我一直感兴趣的是另一个问题, 真正的谜团,而不是他们是如何工作的, 其实安慰剂为什么工作。 |
| 1:16 | If you think about it from the point of view of evolution, a placebo effect is actually rather paradoxical. | 如果你从进化的角度来考虑, 安慰剂效应实际上相当矛盾。 |
| 1:22 | Because when we get better under the influence of a placebo, of course we're curing ourselves. | 因为当我们在安慰剂的影响下好起来时, 我们当然在治疗自己。 |
展开字幕全文(66 条)
| 序号 | 英文 | 中文 |
|---|---|---|
| 1 | The stones are great and a magic power they have. | 石头是伟大的 和魔法的力量,他们拥有。 |
| 2 | Men that are sick fare to that stone and they wash that stone and with that water bathe away their sickness. | 生病的人去那块石头 洗了那块石头 水洗了他们的病 |
| 3 | The placebo effect has been known about for ages and always been considered hugely important in the history of medicine. | 安慰剂效应已久闻名于世,在医学史上始终被认为是极其重要的. |
| 4 | The great monument Stonehenge may actually have been a kind of placebo hospital, a place to which people came in order to receive faith cures. | 伟大的纪念碑巨石阵可能其实是一类安慰剂医院,人们为了获得信仰治疗而来的地方. |
| 5 | What they did we believe is to touch the stones and through them absorb as they believed some magically potent medicine. | 我们所相信的就是触摸石头,通过石头吸收 因为他们相信一些神奇的药。 |
| 6 | But it's only recently that science has begun to get to grips with what's actually going on when people respond to placebo treatments by reducing their sense of pain. | 但直到最近,科学才开始控制 当人们通过降低痛苦感来应对安慰剂治疗时, 实际发生的事情。 |
| 7 | The placebo effect involves the use of the endogenous opiates, our own internal painkillers, a drug rather like morphine which we release in order to control pain. | 安慰剂效应涉及使用内生阿片剂,即我们自己的内止痛药,是一种药物,类似于我们为了控制疼痛而释放的吗啡。 |
| 8 | What's always interested me though is the other question, the real mystery, not how they work, actually why placebos work. | 但我一直感兴趣的是另一个问题, 真正的谜团,而不是他们是如何工作的, 其实安慰剂为什么工作。 |
| 9 | If you think about it from the point of view of evolution, a placebo effect is actually rather paradoxical. | 如果你从进化的角度来考虑, 安慰剂效应实际上相当矛盾。 |
| 10 | Because when we get better under the influence of a placebo, of course we're curing ourselves. | 因为当我们在安慰剂的影响下好起来时, 我们当然在治疗自己。 |
| 11 | That's what a placebo is by definition. | 这就是安慰剂的定义。 |
| 12 | It's an inert substance. | 它是惰性物质. |
| 13 | But if we can cure ourselves of an illness, then why don't we just do it? | 但是如果我们能治好自己的疾病,那我们为什么不直接做呢? |
| 14 | Why don't we just get on with it? | 我们为什么不继续呢? |
| 15 | Why do we need to wait for permission from a sugar pill or a quack doctor or a snake oil? | 为何要等待糖丸或石膏医生或蛇油的许可? |
| 16 | The only reason we don't, and this must be the explanation, is that it isn't actually in our interests to cure ourselves immediately, whatever the circumstances. | 我们不这样做的唯一原因, 一定是这个解释, 是因为不管在什么情况下, 立即治疗自己并不符合我们的利益。 |
| 17 | Lots of the things we count as illness, pain or fever or nausea for that matter, are not actually illnesses in their own right. | 我们所认为的很多疾病, 疼痛或发烧或恶心 本身并不是疾病。 |
| 18 | They're the vulved defences which we put up against illness. | 它们是我们用来防病的防守 |
| 19 | And of course we don't want to undermine them. | 当然我们不想破坏他们 |
| 20 | We don't want to lose pain when in fact it's protecting us from further injury. | 我们不想失去痛苦 当它实际上保护了我们免于进一步伤害。 |
| 21 | We don't want to stop feeling sick when our bodies are full of toxins. | 当我们身体充满毒素的时候 我们不想停止生病的感觉 |
| 22 | We don't want to relax a fever when we've got bacteria to deal with. | 我们不想在有细菌时放松发烧. |
| 23 | We can't stand the high temperatures which we're developing as a defence in our own body. | 我们无法忍受高温 我们发展成为自己身体的防御系统 |
| 24 | So let's think about the costs and the benefits of, let's say, feeling pain. | 因此,让我们来考虑一下痛苦的代价和好处。 |
| 25 | A little boy falls over in the playground and badly bruises and grazes his knee. | 一个小男孩在操场上摔倒,伤势严重,膝盖受创。 |
| 26 | It hurts. | 痛甚. 师曰. |
| 27 | He cries. | 他哭着 |
| 28 | He sits there and waits for help. | 他坐在那里等待帮助。 |
| 29 | That's a very adaptive response. | 这是一个非常适应性的反应。 |
| 30 | The pain is bringing benefits. | 痛苦带来了好处。 |
| 31 | It's going to stop him making things worse. | 这会阻止他把事情弄得更糟 |
| 32 | It's going to stop him opening up the wound. | 它会阻止他打开伤口。 |
| 33 | It's also going to summon help. | 亦将召救. |
| 34 | But of course it's also considerably a costly thing to do. | 但当然,它也是一件相当昂贵的事情。 |
| 35 | If that pain continues too long, you know, he's not going to be able to get on with his life. | 如果这种痛苦持续太久, 你知道,他不会 能够继续他的生活。 |
| 36 | He's not going to be able to feed himself. | 亦不能自供养. |
| 37 | He's not going to be able to run away from a predator if one turned up. | 如果有人出现,他就无法逃离掠食者。 |
| 38 | Now his mother turns up, takes him in her arms, kisses it better. | 现在他的母亲出现了,把他抱在怀里,吻得更好. |
| 39 | He feels safe now and he doesn't actually need to feel the pain to the extent he did to protect himself. | 他现在觉得安全了 他不需要像保护自己那样 感受到痛苦 |
| 40 | He's going to be protected by his family from now on. | 从此受眷属护. |
| 41 | The effect of that is that suddenly the benefits of the pain have been reduced. | 其效果是疼痛带来的惠益突然减少。 |
| 42 | It's not essential anymore. | 这已经不重要了 |
| 43 | His mother has allowed him to readjust the equation. | 他的母亲允许他重新调整方程式。 |
| 44 | And now the benefit of the pain goes down. | 而今苦乐之益渐减. |
| 45 | The cost of the pain exceeds the benefit and the pain reduces. | 疼痛的代价超过好处,疼痛减少. |
| 46 | Okay, so that's when his mother turns up. | 好吧,这就是他妈妈出现的时候。 |
| 47 | She's a genuine safety signal. | 她是一个真正的安全信号。 |
| 48 | But suppose now that some quite spurious signal turns up. | 但假设现在出现了一些很虚假的信号。 |
| 49 | Supposing he sees a poster up on the wall saying, | 假如他看到墙上的海报说 |
| 50 | Okay, you're being looked after by the great god Elmo. | 好吧,你正在被伟大的神爱莫照顾。 |
| 51 | Don't worry about anything. | 什么都别担心 |
| 52 | You'll be all right. | 你会没事的。 |
| 53 | Elmo will look after you. | 艾莫会照顾你的 |
| 54 | Now that's fake information. | 现在,这是假信息。 |
| 55 | And nonetheless, the boy may respond just as he would to the genuine information that he's in safe hands by reducing his pain. | 不过,这孩子可能会像他一样 回应真正的消息,即他通过减轻痛苦而安全地掌握在手中。 |
| 56 | In effect, he'll have responded to a placebo medicine. | 实际上,他会对安慰剂药做出反应。 |
| 57 | We could be receiving a false safety signal. | 我们可能收到假安全信号 |
| 58 | And it's still going to be just as effective in getting us to reduce our pain or to reduce our fever. | 并且它仍然会同样有效地 帮助我们减轻痛苦或降低发烧。 |
| 59 | Now you'll see from the story I've been telling that actually I'm saying that placebos are a mistake. | 从我所讲的故事中你可以看到, 其实我是说安慰剂是个错误。 |
| 60 | We're doing something which is potentially maladaptive when we respond to false information in order to lower our guard, let down our defenses. | 我们正在做一些可能不适应的事情 当我们回应虚假信息 为了降低我们的警惕, 放松我们的防御。 |
| 61 | And I think we have to accept that in the past, evolutionary past, that indeed might have been a very bad idea. | 我认为我们必须接受,在过去, 进化的过去, 这是一个非常糟糕的想法。 |
| 62 | We'd have been curing ourselves prematurely when it wasn't actually safe to do so. | 如果真的不安全的话,我们就会早点治好自己。 |
| 63 | Today, we have much greater levels of social support, good diets, warmth, comfort, access to medications and so on. | 今天,我们的社会支持程度要高得多,饮食好,温暖,舒适,有获得药品的机会等等. |
| 64 | And so we really can afford to let down our guard in ways in which we couldn't in the past. | 这样我们才能以过去无法承受的方式 放松警惕 |
| 65 | We don't need to be as careful as we used to be. | 我们不需要像以前那样小心 |
| 66 | And so, indeed, a dose of contrived optimism, which is basically what placebos provide, could be just what the doctor ordered. | 所以,事实上,一剂精心构思的乐观, 这基本上是安慰剂提供的, 可能是医生点的。 |
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