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哈以俄乌最大赢家可能是…改变历史的医学突破?

字幕摘录

时间英文中文
0:04Good morning, good afternoon, good evening, everyone, wherever you are.早上好,下午好,晚上好,大家好,无论你们在哪里
0:08Welcome to this Yale Center Beijing event on the book, The Masters of Medicine.欢迎来到耶鲁中心的北京活动 这本书,医学大师。
0:15I'm Carolee Rafferty, the executive director of Yale Center Beijing and also Yale College我是北京耶鲁中心 以及耶鲁学院的执行主任卡罗莉·拉费蒂
0:21Class of 2000.2000级.
0:24And I'm delighted to have a distant cousin, Dr. Andrew Lam here, a retinate surgeon and我很高兴有一位远房的表妹 安德鲁·林博士 重症外科医生
0:33award-winning author of the book that we'll be speaking about today to speak about the获奖的书作者 我们将谈论今天 关于
0:39history of medicine and how medicine is actually the only winner in wars, which I thought was医学史 医学是如何成为战争中唯一赢家的
0:48a very catchy title.标题不错
0:50A bit of a bit of background, Andrew, Dr. Andrew Lam, he was class of 1998 at Yale有一点背景,安德鲁, 安德鲁·林博士,他是1998年在耶鲁的班级
0:59College.学院.
展开字幕全文(776 条)
序号英文中文
1Good morning, good afternoon, good evening, everyone, wherever you are.早上好,下午好,晚上好,大家好,无论你们在哪里
2Welcome to this Yale Center Beijing event on the book, The Masters of Medicine.欢迎来到耶鲁中心的北京活动 这本书,医学大师。
3I'm Carolee Rafferty, the executive director of Yale Center Beijing and also Yale College我是北京耶鲁中心 以及耶鲁学院的执行主任卡罗莉·拉费蒂
4Class of 2000.2000级.
5And I'm delighted to have a distant cousin, Dr. Andrew Lam here, a retinate surgeon and我很高兴有一位远房的表妹 安德鲁·林博士 重症外科医生
6award-winning author of the book that we'll be speaking about today to speak about the获奖的书作者 我们将谈论今天 关于
7history of medicine and how medicine is actually the only winner in wars, which I thought was医学史 医学是如何成为战争中唯一赢家的
8a very catchy title.标题不错
9A bit of a bit of background, Andrew, Dr. Andrew Lam, he was class of 1998 at Yale有一点背景,安德鲁, 安德鲁·林博士,他是1998年在耶鲁的班级
10College.学院.
11His major was history.他的少校是历史
12Besides being a retina surgeon, he's he has authored a number of books, including Saving除了做视网膜外科医生之外,他还写了几本书,包括"拯救"
13Sight, an Amazon bestseller about his surgical career and two novels about the Second World影视,亚马逊畅销书 关于他的外科生涯 和两部关于第二世界的小说
14War, one called Two Sons of China and another called Repentance.战争,一个叫中国的"两个儿子",另一个叫"忏悔".
15Before attending medical school, he was at Yale and his writing has appeared in many在上医学院之前 他在耶鲁大学 他的写作已经出现在很多
16publications, including The New York Times, Washington Post and USA Today.出版物,包括《纽约时报》、《华盛顿邮报》和《今日美国》。
17He's currently also an assistant professor at the University of Massachusetts Medical他目前也是马萨诸塞大学医学院的助理教授
18School.学校
19I know that he has given this talk to audiences.我知道,他已经给 观众的谈话。
20As wide ranging as academic to the Smithsonian Museum, lovers or followers.广至学术至史密森尼博物馆,爱好者或追随者.
21So I'm very delighted to be welcoming him to this Yale Center Beijing talk.所以我非常高兴地欢迎他参加耶鲁中心北京演讲.
22So, Andrew, going to you and please feel free to share your screen.所以,安德鲁,去你那里 请随意分享你的屏幕。
23Thank you.谢谢
24Well, thanks a lot.谢谢
25Oh, sorry.对不起
26{\fn黑体\fs22\bord1\shad0\3aHBE\4aH00\fscx67\fscy66\2cHFFFFFF\3cH808080}请随便打开你的相机 {\fn黑体\fs22\bord1\shad0\3aHBE\4aH00\fscx67\fscy66\2cHFFFFFF\3cH808080}这样我们就能看清安德鲁能是谁
27see who he's interacting with.看看他在和谁互动
28Thank you.谢谢
29Yeah, I'll share my screen in a second.是的,我马上就会分享我的屏幕。
30Thanks so much for that kind introduction.谢谢你的介绍
31And thank you all for being here and spending some of your Friday evening with me.感谢大家来这 和我度过周五的夜晚
32I love talking about two of my favorite subjects, which are World War Two history and我喜欢谈论我最喜欢的两个主题, 即二战的历史和
33medicine.
34You know, is my day job as as Carol mentioned, I'm a retina surgeon, which你知道,这是我的日常工作 正如卡罗尔提到, 我是个视网膜外科医生,
35means I spend most of my time trying to save sight from serious conditions like retinal意思是我大部分时间都在努力 避免视网膜等严重疾病
36detachments and diabetic retinopathy and macular holes and macular degeneration.分泌和糖尿病的肾上腺病 和乳腺洞和乳腺退化
37But anyone who knows me knows that my first love was history.但认识我的人都知道我的初恋是历史
38And I'm sure there's many history buffs in the audience here tonight as well.我敢肯定,有很多历史布法 今晚在这里的观众。
39You know, tonight, I thought I would just briefly tell you a little bit about how I你知道,今晚,我想我只是 简短地告诉你一些关于我是如何
40became an author, because when I left Yale, I didn't think this would ever happen to成为一名作家,因为当我离开耶鲁时,我没想到会发生这种事
41me.来啊
42Certainly, I think my English teachers in high school were shocked that I became an当然,我想我的英语老师在高中 震惊地认为,我成为一个
43author because I wasn't really the most assiduous English student, for example.因为我不是最勤奋的英语学生
44But I will tell that story.但我会讲这个故事。
45And then I want to really share a couple of amazing history stories with you guys, which然后我想和你们分享一些惊人的历史故事
46I think will inspire everyone.我认为会激励每个人。
47So when I went to Yale twenty five years ago, it seems like yesterday, but it was quite所以,当我去耶鲁 25年前, 它似乎像昨天,
48a while, I guess.我想是一会儿吧
49I'm Asian history and my focus was military history and U.S.-Chinese我是亚洲历史,我的焦点是军事历史和美国华人
50relations.关系
51And my mentor was this professor named Jonathan Spence, who really, in我的导师是一位叫乔纳森·斯彭斯的教授, 他真的,在
52retrospect, changed my life in some ways.回想一下 改变了我的生活
53You know, he was I know there's probably a lot of younger people who don't even have你知道,他是,我知道 可能有很多年轻人 谁甚至没有
54any idea who he was, but he was a famous history professor of Chinese history.但他是著名的中国历史教授
55And he he was my mentor and he was my senior thesis advisor.他是我的导师 他是我的高级论文顾问
56And I wrote my senior essay on the Flying Tigers, which were, as you probably know,我写了一篇关于飞虎队的论文 如你所知
57American mercenary pilots who flew for China against Japan during World War Two before二战期间飞往中国抗日的美国雇佣军飞行员
58Pearl Harbor, actually.其实是珍珠港
59And, you know, under under his influence, I actually did think在他的影响下 我确实认为
60about going to grad school in history and becoming a history professor.成为历史教授
61But I also had a father who was a cardiologist.但我还有一个父亲是心脏病学家。
62And growing up, you could I grew up in central Illinois and he made a you know, you在伊利诺伊州中部长大,他做了一个 你知道,你
63could see he made a really big impact in our community.可以看到他在我们的社区里 产生了巨大的影响
64You know, he was saving lives.你知道,他是在拯救生命。
65People with strangers would stop me in the street as a有陌生人的人会阻止我在街上
66kid and ask me if I was going to be a great doctor like my dad.孩子,问我是不是要 像我爸爸一样成为一个伟大的医生。
67And so these kind of indelible moments made me realize that being a doctor could be a所以这些不可磨灭的瞬间 让我意识到当医生可能是
68really fulfilling career.真正的成就事业。
69And so I actually went to medical school.所以我真的去了医学院。
70But I remember the moment when I said to myself, I wonder if I could become an author.但我记得,当我对自己说, 我不知道我是否可以成为一个作者。
71And ironically, it happened in an emergency room in my second year of residency in the具有讽刺意味的是,它发生在一个急诊室里 在我住过的第二年里
72middle of the night.夜半时.
73I literally remember it was like 2 a.m.我还记得那就像凌晨2点一样
74And finally, the flow of patients had started to die down, but I couldn't leave.最后,病人的流量开始下降, 但我不能离开。
75So I was just sitting there at the desk kind of daydreaming.所以我就坐在桌子上做白日梦
76And I had to say this thought that I am sure has never happened in the history of an我不得不说,这个想法 我敢肯定,在历史上从来没有发生过
77emergency room.急诊室
78I thought to myself, it's such a pity I can't share all the stuff I我对自己想, 真可惜我不能分享所有的东西
79know about World War Two and China with people.了解二战和中国与人的关系.
80You know, I had studied this a lot in college and I really felt like China was like this你知道,我在大学里学过很多东西 我真的觉得中国是这样的
81unmind aspect of World War Two that a lot of at least American readers didn't know至少美国读者不知道
82enough about.够了
83You know, they may know a lot about D-Day or Pearl Harbor or Guadalcanal,你知道,他们可能知道很多关于D -Day或珍珠港或瓜达尔卡纳尔,
84but they didn't really realize or didn't know about all the American Foreign Service但他们并没有真正意识到 或不知道所有美国外交部
85officers and men who went to China.去中国的军官和人员
86And, you know, frankly, they met, they worked with the nationalists, they helped, they met坦白地说,他们相遇了 他们和民族主义者合作了 他们帮助了他们
87with the communists and all these things that they did in this important theater of the共产主义者和他们在这个重要剧院 所做的一切
88war.战争。
89But I was kind of like, I want to share these this information with people, but I但我有点喜欢, 我想分享这些信息 与人们,但我
90don't have time to write a nonfiction book, you know, because I'm a busy resident.没有时间写一本非虚构的书,你知道, 因为我是一个繁忙的居民。
91I had three little kids and didn't have time to interview veterans or travel to China.我有三个孩子,没有时间采访退伍军人或到中国旅行.
92So I kind of was stuck until I thought that night, what if I wrote a novel?所以,我有点卡住了 直到我想到那晚, 如果我写了一本小说呢?
93You know, let me just start sharing my screen now.现在让我开始分享我的屏幕
94You know, a novel is something I could think up any time I could think about it going to你知道,小说是我随时可以想到的
95work.工作时
96I could think about it when I'm sitting in the ER between patients.我可以考虑一下 当我坐在急诊室 病人之间。
97You know, I didn't really need to do any reading because I had the information I wanted你知道,我真的不需要做任何阅读 因为我有我想要的信息
98to share.共享。
99I watched a lot of war movies, possibly all of them.我看过很多战争电影 可能是所有的
100And I remember thinking, I'm sure I could think of an exciting, epic, romantic war story我记得在想,我相信我可以想到 一个令人兴奋,史诗般,浪漫的战争故事
101and use that as a way to both educate and entertain.用它来教育和娱乐
102And so that's what I did.所以我就这么做了
103I wrote a novel.我写了本小说
104It took many, many years.花了很多年时间
105I got an agent.我有一个经纪人。
106I got a book deal.我有一个书交易。
107And in 2014, that book came out and it was very nice.2014年,那本书出来了,非常不错。
108I put a lot of time into it and it was called Two Sons of China.我投入了很多时间,它被称为"中国的两子".
109And at that point, you realize, you know, you've got a literary agent.那时,你意识到,你知道, 你有一个文学代理人。
110And when you have an agent, you suddenly spend all of your time thinking about what else当你有经纪人时,你突然 花你所有的时间去思考什么
111could I write about, you know, because you now have something very valuable and that's我可以写作,你知道, 因为你现在有 非常有价值的东西,这就是
112access, OK, access to editors and publishers.访问编辑和出版商
113And I thought to myself, gosh, I'm a very historically minded ophthalmologist.我对自己想,我的眼科医生 很有历史意义。
114I have a great idea because there are so many great stories of medical discovery and我有一个伟大的想法 因为有很多伟大的故事 关于医学发现,
115ophthalmology, many of which have to do with World War Two.眼科,很多与二战有关.
116And these are stories of unsung heroes who basically suffered, persevered to make这些是无名英雄的故事 他们基本上受苦受难 坚持不懈地创造
117discoveries that changed all their lives and saved sight.这些发现改变了他们的一生 拯救了视力
118And I remember I went to my agent and I said on the phone, I've got a great idea.我记得我去找我的经纪人 电话里说我有个好主意
119I want to write a book about ophthalmology's heroes.我想写一本关于眼科英雄的书
120And there was complete silence.并有完全的沉默。
121And I knew this was not good, but I just waited for her to respond.我知道这不好 但我只是等着她回应
122And she finally said very tactfully, you know, I really just don't think this is going to她终于说得很巧妙了,你知道, 我真的不认为这会
123work for us.为我们工作。
124And I said, why not?我说,为什么不呢?
125And she just said, I think that the general public is just not going to be interested in她刚刚说,我认为 公众只是不会感兴趣
126a book about ophthalmological history.一本关于眼科史的书。
127So I was crestfallen and it took me a little while to get over my disappointment.于是我跌倒了,我花了一点时间来克服我的失望。
128But I also was I also realized she was right.但我也意识到她是对的
129You know, her job is to make money selling books.她的工作是赚钱卖书
130She doesn't want to waste her time with a book that's not going to be successful.她不想浪费她的时间 一本不会成功的书
131I guess I shouldn't waste my time writing a book that people aren't going to read.我想我不应该浪费我的时间 写一本人们不会读的书。
132But I wanted so strongly to share these incredible stories with people.但我非常强烈地希望与人们分享这些不可思议的故事。
133I just thought really hard about what I could do to make it more marketable.我只是在想我能做些什么 使它更适合市场
134Right.
135So then I thought, well, what if I blended my personal story as a surgeon所以我想,嗯,如果我混合 我的个人故事作为一个外科医生
136in training with the historical story so I could bring people into the operating room在训练 历史故事 所以我可以带人 进入手术室
137to show them what it's like to try to save sight or maybe more interestingly, what it's让他们知道什么是 试图拯救视线, 或也许更有趣的是,它是什么
138like to come up against terrible complications that we sometimes have and not even know喜欢面对可怕的复杂 我们有时有,甚至不知道
139exactly what to do or sometimes all the options are bad and you just have to choose the确切的是什么 或有时所有的选择都是坏的 你只需要选择
140least worst one.至少最差的一个。
141And that blending of my story is probably what made the book as我的故事的融合 可能是这本书
142successful as it was.已经成功了
143It was called Saving Sight.叫做"拯救视觉"
144It actually got a book deal so fast, it came out before my novel, even though I had虽然我写了
145written the novel many years before.写小说很多年前。
146And ever since Saving Sight came out, people told me, readers, editors, you should自从《拯救视力》出来后 人们告诉我,读者,编辑,你应该
147do that for all of medicine.这样做是为了所有的药物。
148You know, you should find all of these unsung medical heroes who nobody knows about你知道,你应该找到所有这些 无人知晓的医学英雄
149with people who aren't well known but deserve to be.和那些不为人知但值得有的人在一起
150And that I knew that was a good idea.我知道这是一个好主意。
151But along the way, I had also been very involved in trying to tell another incredible但一路走来,我也一直非常参与 试图告诉另一个不可思议的,
152American story.美国故事.
153And that is about the Japanese Americans who fought in World War II这是关于参加二战的美国日本人
154in Europe with incredible valor while some of them had families incarcerated in camps在欧洲 有着令人难以置信的勇气 而他们中的一些人有 家庭监禁在难民营
155unjustly like Manzanar at home.就像家里的曼扎纳一样
156And that was a novel called Repentance that came out in 2019.2019年出版的名为"忏悔"的小说.
157But, you know, during this time, I was still kind of thinking this idea for a medical但是,你知道,在这期间, 我仍然在想这个想法 对于医学
158history book is going to be a good one.历史书将成佳作.
159And during the pandemic, I finally had time to start reading about other aspects of在这场大流行期间 我终于有时间开始读到
160medicine.
161So, you know, I read about cardiology kind of an homage to my dad, I guess.所以,你知道,我读 关于心脏病学 一种向我爸爸的致敬,我想。
162And I had been I was blown away.我被炸飞了
163You know, I had been a pretty arrogant ophthalmologist.你知道,我是一个相当傲慢的眼科医生。
164I thought that all the best stories of discovery were in my field.我以为所有最好的发现故事 都是在我的领域。
165I mean, some of the stories of the things that were invented to save sight had to do我的意思是,一些故事 事情被发明 拯救视力
166with the Battle of Britain and like pilots getting shot down with plexiglass in their与不列颠之战 和像飞行员被击落 在他们的双镜
167eyes and like that invented that led to the invention of the artificial lens and stuff.眼睛和这样的发明 导致了人工镜头和东西的发明。
168And so there's great stories.故有大经.
169But cardiology blew me away.但心脏病学把我吓跑了
170I mean, the long suffering people who risked their own lives sometimes to develop我的意思是,长期受苦的人 谁冒着生命危险有时发展
171cardiac catheterization or cardiac surgery just was amazing.心脏导管化或心脏手术是惊人的。
172And then I read about the discovery of insulin and how these four Canadian discoverers然后我读到了胰岛素的发现 以及这四个加拿大的发现者
173hated each other so much.恨对方这么多。
174One of them almost refused the Nobel Prize because he was just其中一个几乎拒绝了诺贝尔奖 因为他只是
175so incensed that a co-discoverer was also going to get one.以至于一个共同发现者也会得到一个
176He just felt that his contribution had so much like outshined this other guy.他只是觉得他的贡献 是如此的像辉煌 超过另一个家伙。
177And I realized that these doctors who saved millions of lives were so like guilty我意识到这些拯救了数百万生命的医生 简直就是有罪的
178of just human fallibility, envy, you know, jealousy and just like self-interest.只是人类的谬误, 嫉妒,你知道, 嫉妒,就像自我利益。
179And I was just totally hooked.我完全上瘾了
180These stories had so much drama.这些故事太戏剧化了
181And that is what became the Masters of Medicine.这就是成为医学大师。
182So thanks for listening to just how I became an author, basically.基本上,谢谢大家聆听我如何成为作家。
183And I'd love to now jump into telling you a couple of great stories.现在我想告诉你几个好故事
184These are stories that are about World War Two.这些都是关于二战的故事。
185And my favorite adage is the only only winner in war is medicine.我最喜欢的格言是战争中唯一赢家是医学
186That's true.没错
187Right.
188So true.没错
189And tonight, I want to tell you about how a wounded soldier during D-Day helped今晚,我想告诉你 一个受伤的士兵在D日是如何帮助的
190inaugurate the field of cardiac surgery.开创心脏手术领域.
191Because I just think operating on the heart is just such an incredible, miraculous thing.因为我觉得在心脏上做手术 是个不可思议的奇迹
192And a second story will be about how a disastrous Luftwaffe bombing raid in Italy第二个故事是 如何在意大利进行一场灾难性的德国空军轰炸
193led to the first cancer chemotherapy drug, which has changed the lives of so many people.导致了第一种癌症化疗药物,它改变了这么多人的生活.
194So let's begin.我们开始吧
195So this first story is about the heart and operating on it.所以这个第一个故事是关于心脏和操作的。
196So think about the heart.故为心想.
197It's constantly moving.不断动静.
198It's buried in the center, deep in the center of the chest behind a wall of ribs.它被埋在中央,胸前中央深处的肋骨壁后方.
199And you can see why for millennia, the idea of approaching it, exposing it,你可以看到为什么千年来, 接近它的想法, 揭露它,
200operating on it, operating inside it was impossible.操作它,操作里面是不可能的。
201Right.
202It would take only a truly desperate situation for any surgeon.任何外科医生都只能面对真正的绝望
203Even think about it.乃至想着.
204It would be insane to think about doing this.考虑这样做是疯了
205Right.
206Well, enter World War Two.好吧,进入二战。
207As you can imagine, the war produced a plethora of these你可以想象,战争产生了大量的这些
208gruesome injuries of a nature that doctors and surgeons had never encountered in civilian life.在平民生活中,医生和外科医生从未遇到过可怕的伤害。
209So there was this one surgeon named Dwight Harkin.有个叫德怀特·哈金的外科医生
210He was from Iowa.他是爱荷华州人
211So a fellow midwesterner like me.像我这样的中西部人
212So I knew I would like him when I started reading about him.所以我知道当我开始读到他的时候 我会喜欢他
213And he was stationed in an army hospital near London and he had trained at Harvard Medical School.而他驻扎在伦敦附近的一家陆军医院,曾在哈佛医学院受训.
214And he went over overseas during the war.战争期间他去了海外
215And he sometimes encountered these men whose chest had been kind of blown apart by like bomb blasts or shrapnel.他有时遇到这些人,他们的胸部被炸弹爆炸或弹片炸裂。
216And sometimes these men had pieces of metal that had punctured the heart wall,有时这些人有金属碎片 刺穿心脏壁,
217but had plugged the hole that they had made so that these soldiers were still alive.却堵住了他们挖的洞 让这些士兵还活着
218They were languishing, but they were kind of close to death.他们正在受苦,但他们 有点接近死亡。
219You know, they were they were died.他们死了
220Nothing was done from slow exsanguination.缓缓的外出没有做任何事情。
221Or sometimes when you have like metal surfaces in the bloodstream,或者有时当你有 像金属表面在血液中,
222you get bullet clots that lead to strokes and you can die from that.你得到子弹块 导致中风,你可以死。
223So he wanted to do something to help these young men.所以他想做点什么来帮助这些年轻人.
224But he knew what would happen the second that you pull out the metal from a beating heart.但他知道一旦你从心跳中拔出金属 会发生什么
225You're going to have incredible bleeding under pressure, right?你会在压力下出血,对吧?
226It's going to be impossible.这不可能
227And, you know, if you've ever, you know, the first time I saw heart surgery,而且,你知道,如果你曾经,你知道, 我第一次看到心脏手术,
228I was like thinking to myself, this is incredible.我就像在想,这是不可思议的。
229God did not intend for us to be able to do this.上帝并不打算让我们做到这一点。
230But now you can just watch it on YouTube.但现在你可以在YouTube上看
231So if you've ever watched heart surgery, you know that operating in the heart is literally operating in a hole.所以,如果你看过心脏手术, 你知道心脏的手术 完全是一个洞。
232And if you have uncontrolled bleeding in that hole,如果你在那个洞里无控制地流血
233you quickly lose all your visibility and there's no way you can do anything.你很快会失去你的能见度 也不可能做任何事
234So Harkin knew that if he was going to try to do something here,所以哈金知道 如果他想在这里做点什么
235he was going to have to do fine.他本来要好好的
236Think of a novel way or a new way to operate on or suture the heart.想想新颖的方法 或新的操作方式 或缝合心脏。
237Well, on D-Day, this is June 6, 1944, he actually tried a new method.嗯,在D -Day,这是1944年6月6日, 他实际上尝试了一种新的方法。
238A soldier was brought to him with a terrible wound.一名士兵被带去,伤势严重。
239Piece of metal was in his heart, punctured his heart and was plugging the hole.金属碎片在他的心脏,刺穿他的心脏,并插孔。
240His idea was to pull out the metal and immediately stick his finger in the hole.他的主意是拔出金属,立即将手指插进洞里.
241It's not that sophisticated.没那么复杂
242But, you know, he thought it was this finger,但是,你知道,他觉得这是这个手指,
243literally a finger in the dike strategy might give him enough precious seconds从字面上说,一个手指 在沉淀策略 可能给他足够的珍贵秒
244to pass two or three sutures so he could close the hole.通过两三个缝合 这样他就可以关闭洞。
245But, you know, still very difficult to do in a bleeding heart.但是,你知道,仍然很难做 在流血的心脏。
246So he decided to proceed.因此,他决定继续工作。
247In this patient, he opened the chest, he spread the ribs,在这个病人中,他打开了胸口,把肋骨伸开,
248he entered the pericardial sac,他进入心腹,
249and he could see the metal bobbing up and down with every beat of the heart.他可以看到金属弹跳 与每一个心脏跳动。
250He grabbed it with a clamp and yanked it out and stuck his finger in the hole.他用钳子抓住了它,然后把手指伸到洞里。
251And imagine the tension at this moment.想象一下此刻的紧张状况
252You know, you have to understand nobody to this point你知道,你必须明白 没有人到这一点
253had ever done like a premeditated operation on a beating heart before.曾经做 像一个预谋的手术 在心脏跳动。
254Okay, again, the heart was inviolate.好吧,再次,心脏是不可侵犯的。
255The surgeon should never approach the heart was the thinking before this.外科医生不应该靠近心脏 之前是想的
256Though I can't compare with his first try at this,虽然我无法比拟他的第一次尝试
257I can tell you sometimes when I'm operating,我可以告诉你,有时当我在手术,
258you know, there are moments of pure stress bordering on panic.你知道,有些时刻 纯粹的压力 接近恐慌。
259You know, this usually is happening when I'm trying to fix a renal detachment.你知道,这通常发生 当我试图修复 肾上腺分解。
260And the visibility for what I'm trying to do is going badly我试图做的事的能见度是糟糕的
261because the cornea is getting too hazy, which means I got to work faster.因为角膜太阴郁了 这意味着我需要更快地工作
262But ironically, it's even harder to work faster because I can't see what I'm doing.但具有讽刺意味的是,因为我看不到自己在做什么,所以更难更快地工作.
263Or sometimes people will get artificial lenses after cataract surgery有时候白内障手术后 别人会用人造镜头
264and they'll fall into the back of the eye and I've got to fish them out.然后他们就会掉进眼睛的后面 而我得把他们捞出来
265And they're lying on the retina and I'm terrified of damaging the retina他们躺在视网膜上 我害怕破坏视网膜
266by like touching it or manipulating things and that I'll make things worse.就像摸它或者操纵东西 我会把事情弄得更糟
267And those are times when my heart is racing and it's quite nerve wracking.那些时候,我的心在竞速, 和它相当的神经崩溃。
268And so, you know, I'm pretty sure Dwight Harkin, knowing how he might have felt,所以,你知道,我敢肯定,德怀特·哈金, 知道他的感受,
269must have had sweat dripping down his brow when he's got his finger inside this soldier's heart.当他把手指伸进这名士兵的心脏里时 他的眉毛一定流了汗
270But guess what?但你知道吗?
271It actually seemed to be working.这似乎在起作用。
272You know, he was able to stem the blood and was able to pass a suture,你知道,他能够阻止血液 并能够通过缝合,
273then another suture to kind of close this hole.然后又缝合了一道缝合洞
274And the only moment of dismay occurred when the third suture went through a finger of his glove唯一令人沮丧的一刻 发生在第三次缝合穿过他的手套的手指
275and he found himself sutured to a beating heart.他发现自己缝合到一颗跳动的心脏。
276We know this because he wrote a letter to his wife about this operation,我们知道这一点 因为他写了一封信给他妻子 关于这次行动,
277this fateful operation, and it was just incredible.这场命中注定的行动 太不可思议了
278So he cut himself free and believe it or not, the surgery worked.所以他把自己割开 相信与否 手术成功了
279The soldier survived.该士兵幸存下来。
280Amazing, right?厉害吧?
281The first, an actual strategy and plan to operate on a beating heart.第一,在心脏跳动上操作的实际战略和计划。
282Well, he was a smart guy.嗯,他是一个聪明的家伙。
283He made improvement on his techniques.他的技巧得到了改进.
284He said to himself, well, wait a second.他对自己说,等一下
285What if before I pulled out the metal, I made, I placed a,如果在我拿出金属之前 我做了一个...
286I pre-placed a ring of sutures around the metal.我预先在金属周围放置了一圈缝合物
287That way I could yank out the metal and just pull on the string.这样我就能拔出金属,拉上绳子
288And then the hole would just close up fast.然后洞就会迅速关闭
289Smart, huh?聪明,是吧?
290We're just getting started.我们才刚刚开始
291This guy used his methods and improved them这家伙用他的方法改进了
292and managed to remove the metal fragments from parts of over a dozen soldiers during the war.并在战争期间设法从十几名士兵的部位清除金属碎片。
293Only because of World War II and the number of men he encountered with this只因为二战和他遇到的人数
294manner of cardiac wound, could he have practiced and improved his technique.心脏受伤的方式, 他是否已经实践和改善了他的技术。
295So now I'm going to tell you how this changed all our lives for the better.所以,现在我要告诉你,这 如何改变了我们所有的生活 变得更好。
296So let's fast forward to after the war.因此,让我们在战后迅速前进.
297You have to understand that the most common heart disease of that time was something called你必须明白,那个时候最常见的心脏病 是所谓的
298mitral stenosis, which stemmed often from a common childhood illness called rheumatic fever.蛋白质激素化(mitral stenosis),常源于一种常见的儿时疾病,称为风湿热.
299So this is the era before antibiotics.这就是抗生素之前的时代。
300Kids would get this thing called rheumatic fever and they'd get sick孩子会得这种叫风湿热的病
301and then they'd recover and they'd be fine, except that they weren't because然后他们就会康复,他们会好起来, 只是他们不是因为他们
302the inflammation that would happen in their bodies from the infection感染后在体内产生的炎症
303would harm parts of their body, particularly their heart valves.会伤害身体的部位 特别是心脏瓣膜
304And the mitral valve separates, I'm not going to see my arrow,和圆柱阀分离, 我不会看到我的箭,
305the left atrium and the left ventral.左边的阁楼和左边的通风口
306This is the mitral valve and blood is supposed to go from the left atrium to the left ventricle这是顶部的阀门 血液应该从左门到左门
307and then go out the aorta to the rest of the body.然后从主动脉到身体的其余部分
308So the job of the mitral valve is first of all to allow the blood to pass through it entirely,因此,线粒体阀的工作首先是 让血液完全通过它,
309to empty the left atrium.以清空左边的阁楼。
310And then its job is to slam shut so that all the blood gets ejected out the aorta然后它的工作就是关上门 让血液被喷出主动脉
311and does not go backwards into the left atrium.而不向左转。
312Well, the problem is with the scarring and inflammation and问题是伤疤和炎症
313hotness and thickening of the mitral valve that can occur over years of inflammation在多年炎症中可能发生的线粒体阀热度和厚度
314after rheumatic fever, the mitral valve becomes narrowed and it becomes like a bottleneck.在风湿发烧后,顶部阀门变得狭窄,变得像瓶颈.
315So what happens with these young people in the primary of their lives,那么这些年轻人在人生的最初阶段会怎样
316in their 20s and their 30s, the blood in their left atrium would not be able to fully empty20多岁和30多岁时 左房的血液无法完全空空
317and it would just start to back up.它会开始备份。
318And what's behind the left atrium?左边的阁楼后面是什么?
319It's the lungs, because the blood goes from the right side of the heart to the lungs是肺,因为血液从心脏右侧到肺
320and then the left side of the heart.然后是心脏的左侧。
321So these patients would have lungs that would fill up with fluid, fill up with blood,所以这些病人的肺部会充满液体 充满血液
322they wouldn't be able to breathe, they'd be coughing up blood all the time他们无法呼吸, 他们总是咳血
323and they would die in the primary of their lives.他们将在生前就死去。
324And so, you know, there were surgeons who dreamed of doing something所以,你知道, 有外科医生 谁梦想做一些事情
325to do something to help these patients, but what could they do?做点什么来帮助这些病人 但是他们能做什么呢?
326Well, there were two rival surgeons who dreamed of doing something about this.有两个对手的外科医生 梦想着做点什么
327One was Dwight Harkin, who I told you about from World War II,一个是德怀特·哈金 我跟你说过二战时
328but another was named Charles Bailey.但另一个叫查尔斯·贝利
329And Charles Bailey was well known for being incredibly arrogant.而查尔斯·贝利以令人难以置信的傲慢而闻名.
330Okay, he had a crazy idea to try to treat mitral synodes.好吧,他有一个疯狂的主意 试图治疗线粒体。
331He was from Philadelphia.他是费城人
332His idea was to take Harkin's techniques a lot further.他的想法是把哈金的技巧更进一步.
333He wanted to, first of all, make a pursing suture in the left atrium,他想,首先,在左边的阁楼做缝纫
334then make an intentional incision in the center of that suture然后在缝合的中央故意切除
335and then stick his finger in the hole.然后把他的手指插进洞里
336Okay, so that you're familiar with.好吧,这样你熟悉。
337So now he's dreaming, what could I do with my finger in the heart?所以现在他正在做梦,我的手指插进心脏我还能做什么?
338Well, what can we do with our fingers?那么,我们能做什么 用我们的手指?
339One thing we do is just we can poke, right?我们做的一件事就是可以戳一下 对吧?
340We can poke.我们可以戳。
341And literally, that was his idea.从字面上来说,这是他的主意。
342He thought to himself, if I could just poke my finger他自以为是 如果我能插手指
343and maybe wring it around the mitral valve orifice,也许它绕着圆柱形阀门,
344maybe I could like separate the fibro's leaflets也许我可以把传单分开
345and make it function better like it used to be when it was healthy.并让它更好地发挥功能 像它以前是健康的。
346The risks of this were enormous and largely unknown.这样做的风险是巨大的,而且基本上不得而知。
347What if his finger disrupted the heart rhythm如果他的手指打乱了心脏节奏怎么办?
348and caused matricular fibrillation and death?导致乳房纤维化和死亡?
349How would he know how hard to poke or how long to poke?他怎么知道多难戳 或多久戳?
350If he poked enough, he wouldn't.如果他戳得够多,他不会。
351It was just all done blindly.这一切都是盲目的。
352So this is an illustration of what he's trying to do.这就是他想要做的事的例证。
353You can see in this illustration,你可以从这个插图中看到,
354the surgeon has his finger in the left atrium.外科医生的手指在左房
355It's basically his fingers going into the mitral valve orifice.基本上他的手指会进入体阀门
356There's a little pursing suture around his finger.他的手指周围有一根细缝
357There's a little metal rod有个小金属棒
358that takes the vector of the sutures in the same direction使缝合的矢量朝同一方向走
359so they can easily be tightened around his finger这样他们就可以很容易地紧紧地围住他的手指
360to limit blood loss and close at the end of the operation.限制失血,并在手术结束时关闭。
361But this is very deceptive, right?但这很欺骗,对吧?
362Because you can't see any of this.因为你看不到这些
363In real life, this thing is moving.在现实生活中,这个东西正在移动.
364It's full of blood.血气充满.
365There's blood kind of oozing out everywhere.到处都是血
366So it's a really challenging thing.所以这是一个非常具有挑战性的事情。
367But of course, he knew that if he did nothing,当然,他知道,如果他什么都不做,
368his patients were going to die.他的病人会死的
369So in November 1945, this is after the war, remember,所以在1945年11月,这是战后,记住,
370he operated on a patient who was 37 years old.他对一个37岁的病人做了手术
371His name was Walter Stockton.他的名字是沃尔特·斯托克顿。
372His mitral stenosis was so bad,他的脊椎硬化症很严重
373he could barely walk or breathe.他几乎无法走路或呼吸。
374He couldn't walk to the end of the driveway to get his newspaper.他不能走到车道尽头去取他的报纸.
375He was frequently coughing up blood.他经常咳血。
376And Bailey took him to the operation.贝利带他去手术室
377He made an incision in the chest.他胸口割伤了
378He spread the ribs.他张开肋骨。
379He entered the pericardial sac.他进入心腹腔
380He pre-placed his ring of sutures他把缝合的戒指放在前面
381and made an incision and stuck his finger in the hole.然后做了个切口 然后把手指插进洞里
382And now he tries to tighten the suture around his finger现在他试图把手指上的缝合拉紧
383to limit the blood loss.以限制失血。
384And unfortunately, the suture tears through the cardiac muscle不幸的是,缝合的眼泪穿过心脏肌肉
385and pulls out.并抽出来。
386And he's sitting there with one finger in the heart他坐在那,心里只有一根手指
387and one finger holding a string.一根手指握着绳子
388And the blood is gushing, filling up his hole.血流成河 填满了他的洞
389He's working fiercely yet in vain.他工作激烈却徒劳无功
390And in a few minutes, his patient's dead.几分钟后,他的病人就死了
391He didn't even get a chance to try his finger thing in the heart.他甚至没有机会 尝试他的手指的东西在心脏。
392Undeterred, I told you this guy was supremely confident.我告诉过你这家伙非常有信心
393He tried in another patient.他尝试了另一个病人。
394This time, he got his finger in the heart这一次,他的手指在心脏
395and he poked it through the mitral valve.他戳穿了门阀
396And believe it or not, the patient actually survived the surgery信不信由你 病人真的活了下来
397but died within 48 hours.但48小时内就死了
398For these two deaths, Bailey's operating privileges对于这两次死亡,贝利的操作特权
399at Hahnemann Hospital in Philadelphia were revoked.在费城的哈尼曼医院被撤销了
400The chief of cardiology told him,心脏病科主任告诉他,
401it is my Christian duty not to permit you to perform我的基督教义务是不允许你表演
402any more such homicidal operations.任何这样的杀人行动。
403To this, Bailey retorted,对于这个,贝利重新招供,
404it is my Christian duty to perfect this operation.完成这次行动是我的基督教义务
405Nothing could be worse than what mitral stenosis does to people.最糟糕的莫过于 体质激素对人的影响
406Bailey next took his operation贝利接下来做了手术
407to Wilmington Memorial Hospital in nearby Delaware.去附近的特拉华威尔明顿纪念医院
408There he operated on another patient,他对另一个病人做了手术,
409this time his third patient.这次是他第三个病人
410He succeeded in getting his finger in the heart他成功地把手指插入心脏
411and tried to poke around and separate the mitral valve leaflets并试图四处打探 和分离的面膜阀传单
412but he was too forceful.但他太强壮了。
413He was too aggressive.他太冲动了
414He pulled away the mitral valve leaflets.他拉走了面膜阀门传单。
415And if you can believe it, he actually made mitral stenosis worse.如果你能相信的话,他实际上 使蛋白质激素恶化。
416How could you possibly do that?你怎么能这么做?
417He basically tore away the mitral valve leaflets他基本上撕掉了 面膜阀门传单
418so there was basically open communication所以基本上有公开的交流
419between the left atrium and left ventricle.左边的阁楼和左边的通风口之间
420And all the blood in the left ventricle左排气管的血迹
421started going backwards into left atrium.开始往左转
422He had changed, he had converted mitral stenosis他变了,他改了头皮
423into mitral insufficiency.进入线粒体不足。
424Now he's 0 for 3, this patient also died.现在他3分0,这个病人也死了
425In the aftermath, Wilmington Memorial also revoked his privileges之后,威尔明顿纪念馆也取消了他的特权
426and he basically, people started murmuring behind his back他基本上,人们开始 在背后喃喃自语
427and bad mouthing him and he was basically nicknamed和坏嘴 他基本上被昵称
428the butcher in circles in the hospital.医院里的屠夫
429At this point, I can tell you the surgeon who continues on this tack现在,我可以告诉你 外科医生谁继续这个塔克
430is either supremely arrogant, which he probably was,要么是傲慢至极 他可能是,
431or believes so strongly in the rightness of what they're doing或坚信他们的行为的正确性
432that they are willing to endure setbacks and ridicule and deaths他们愿意忍受挫折 嘲笑和死亡
433to see it done.看着它完成。
434As a surgeon myself, I can tell you there's certainly many times作为外科医生,我可以告诉你 肯定有很多次
435when I've tried Hail Mary operations.当我尝试过万福玛利亚手术时
436These always seem somewhat justified这些总是有道理的
437because in my case, they're in eyes that are legally blind因为在我的情况下,他们的眼睛 是合法盲目的
438or going blind.或失明,
439There's almost like you've got nothing to lose,好像你没什么可失去的
440but I can tell you unless it's in a totally improvisational situation但我可以告诉你 除非它完全处于即兴状态
441like in trauma, I have never tried a technique or operation像创伤一样,我从未尝试过技术或手术
442that has never been done before从来没有这样做过
443or certainly nothing that my peers think is insane.或者我的同伴们认为什么是疯狂的。
444To do that, I think I'd have to be either a genius or a madman要做到这一点,我想我要么是天才,要么是疯子
445and I don't think I'm either.我觉得我也不是
446But let's hope Charles Bailey is a genius但愿查尔斯·贝利是个天才
447because he is not going to give up.因为他不会放弃
448He still has operating privileges at two Philadelphia hospitals,他在费城的两家医院还有经营特权
449Philadelphia General and Episcopal Fourth Hospital.费城总医院和主教第四医院.
450But the problem is word of his failures is spreading.但问题是,他的失败正在蔓延。
451He's worried he might have only one more chance他担心他只有一次机会
452to attempt this operation before these institutions ban him as well.在这些机构也禁止他之前尝试这一行动。
453So to maximize the chance of success,所以为了让成功的机会最大化
454he decides to schedule two operations on the same day,他决定在同一天安排两次行动,
455one in the morning at Philadelphia General早上在费城将军
456and one in the afternoon at Episcopal.和下午在主教座堂的一个。
457Even if his first patient dies,即使他第一个病人死了
458he still will be able to rush across town他还是能冲到城里来
459and start the second operation before someone tries to stop him.在有人阻止他之前 开始第二次行动
460This is crazy.这太疯狂了
461He knows that if both patients die, he's likely finished他知道,如果两个病人都死了,他很可能就完了
462because at that point there'll basically be no hospital willing to accept him.因为那时根本就没有医院愿意接受他
463In this day and age, I cannot imagine risking one's career in this way.在这个时代,我无法想象这样冒着职业风险。
464It's just mind-boggling.唯心观心.
465So the first patient at Philadelphia General in the morning dies on the table.所以,第一个病人在费城将军 早上死在桌子上。
466He's 0 for 4.他4分的成绩是0
467No doubt feeling the stress and gravity of the moment,毫无疑问,感觉 压力和严重的时刻,
468he drives over to Episcopal Hospital他开车去主教医院
469where he's going to operate on a 24-year-old housewife named Constance Warner.在那里他要去操作 一个24岁的家庭主妇 名叫康斯坦丝华纳。
470This woman, her rheumatic fever led to such severe heart failure这个女人,她的风湿热导致心脏严重衰竭
471that she could barely move.她几乎无法移动。
472She was unable to care for her young child她不能照顾她的孩子
473and she'd been hospitalized many times.她已经住院很多次了
474This time, to Bailey's relief, the operation seemed to go well.这次对贝利来说 行动似乎进展顺利
475He got his finger inside the heart.他的手指在心脏里。
476He opened up the mitral valve.他打开了顶部阀门。
477No major hemorrhaging occurred.没有发生大出血。
478The patient survived.患者幸存下来.
479He went to check on her the next day.他第二天去检查她。
480She was still alive.她还活着。
481Great sign.伟大的标志。
482The next day, was her breathing a little better?第二天,她的呼吸有好一点吗?
483By the fourth day, she was walking.到了第四天,她还在走路.
484It worked.已经成功了
485It was amazing.这是惊人的。
486Bailey was elated.贝利很高兴。
487His reputation was instantly resurrected.他的名声立即复活。
488He broadcast news of his success.他播报了他成功的消息。
489I'm the greatest.我是最伟大的。
490He took the patient personally on a 1,000-mile train ride to Chicago他亲自带病人去芝加哥1000英里的火车上
491to parade her in front of a big medical meeting在大型医疗会议前给她游行
492just to show everybody, look what I did.只是想让大家看看我做了什么
493He was a hero.他是个英雄
494But meanwhile, I haven't really told you但与此同时,我还没有告诉你
495what Dwight Harkin's been up to all this time in Boston.德怀特·哈金在波士顿所做的一切
496He's also been trying to do a similar surgery many times.他还多次尝试做类似的手术.
497Six days after Bailey's first successful operation,贝利第一次成功行动6天后
498Harkin had his first successful case.哈金办了第一个成功的案子
499Before that, he had tried the operation on six patients在那之前,他已经对6个病人做了手术
500and all six died.六个人都死了
501At that point, the worldwide success of this operation was 2 out of 12.那时,这一行动在全世界的成功率为12次中的2次。
502After the death of one of those patients,在其中一个病人死后
503Harkin returned home despondent.哈金回国后心灰意冷.
504That evening, there was a knock at the door.当晚,有人敲门.
505The caller was a woman who handed over a sealed envelope.来电者是交出密封信封的女人.
506It was a letter from the dead patient.那是死者寄来的信
507The woman was a friend of the patient who had died,那个女人是病人的朋友 死了
508and the patient had made her promise to deliver this letter病人答应送这封信
509if she didn't survive.如果她没活下来
510Harkin opened the letter.哈金打开了这封信
511It said, Dear Dr. Harkin,它说,亲爱的哈金博士,
512Thanks for the chance.谢谢你给我机会
513A small portion of my estate has been left to see我的地产有一小部分被留下看
514that this doesn't happen again.这种事不会再发生
515Can you imagine receiving a note like that?你能想象收到这样的纸条吗?
516If there are any doctors in the audience,如果观众中有医生的话
517I hope to God you never get one.我希望你永远得不到一个。
518And I pray I never get one.我祈祷我从来没有得到过。
519A patient writing you from the grave.一个病人从坟墓里给你写信
520But then think about what it was like to write this letter,但再想想写这封信是什么感觉
521to pen this letter as a patient agreeing to go into an operation作为同意接受手术的病人 写这封信
522that you knew had never been successfully performed你知道从未成功表演
523in the history of the world.在世界历史上。
524And I think that that simply illustrates我认为这只是说明
525the sense of desperation that both the surgeon and patient外科医生和病人的绝望感
526must have felt when facing this hopeless diagnosis.面对这种无望的诊断 一定感觉到了
527Dwight Harkin and Charles Bailey were pioneers of cardiac surgery,德怀特·哈金和查尔斯·贝利是心脏手术的先驱,
528but they failed far more often than they succeeded.但他们失败的次数远超过他们成功的次数。
529To persist in the face of so many deaths面对这么多的死亡 坚持下去
530and heartbreaking setbacks and took supreme courage,和令人心碎的挫折, 和最大的勇气,
531self-confidence, and the ability to bounce back自信和回弹的能力
532after heartbreaking disappointments.在伤心失望之后
533But remember, before them,但记住,在他们之前,
534the heart was not even contemplated心脏甚至没有考虑
535as a thing you could operate on作为你可以操作的东西
536and perform beneficial operations on.并进行有益的操作。
537And because of them, the heart became a viable surgical target.心脏也因此成为了可行的手术目标.
538And that opened the floodgates.这打开了洪水门。
539These successes, these little operations I've told you,这些成功,这些小手术 我告诉过你,
540suddenly got everybody excited突然大家都兴奋起来
541that things we could operate on the heart.我们可以在心脏上操作的东西。
542And within 10 years, they had invented the heart lung machine,十年之内 他们发明了心脏肺机
543which stills the heart so that we can perform proper operations.保持心脏 这样我们才能进行适当的手术
544Shortly thereafter, the first coronary artery bypass surgery此后不久,第一次冠状动脉绕行手术
545was performed in there after the heart transplant in the late 60s.在60年代后期的心脏移植后 在那里做了手术
546And, you know, these guys,而且,你知道,这些人,
547this is a cover of Time magazine in 1957.这是1957年《时代》杂志的封面。
548Charles Bailey was known at the time.查尔斯·贝利是当时的知名人物.
549I've given this talk to large audiences我和广大观众谈过了
550with many illustrious and well-educated people.有许多杰出和受过良好教育的人。
551And only once has anyone ever heard of Charles Bailey before.只有一次有人听说过查尔斯·贝利
552In the question and answer,在问答中,
553if you've ever heard of him before, please tell me.如果你听说过他,请告诉我。
554That person was a cardiac surgeon那个人是心脏外科医生
555who had been a retired cardiac surgeon.曾经是退休心脏外科医生
556And, you know, how much more, I always think to myself,而且,你知道,多远, 我总是想,
557do people like Harkin and Bailey deserve to be known像哈金和贝利这样的人应该被认出来
558than the people we put on pedestals today?比今天我们装踏板的人还好?
559Athletes and celebrities and movie stars.运动员和名人与电影明星.
560You know, these people changed the world,你知道,这些人改变了世界,
561but very few people remember them.但很少有人记得他们。
562And that was, as an author, for this book, Masters of Medicine,作为作者,这本《医学大师》
563it really was one of my primary motivations这真的是我的主要动机之一
564in sharing their stories,分享他们的故事,
565to make these people who aren't well-known but deserve to be让这些人不为人所知,但应该成为
566and share their, like, more well-known among readers.并分享他们一样, 更著名的读者。
567So I'd like to now move on to briefly one more tale from World War II.所以我现在想再简略地谈谈二战的一个故事。
568And this story starts with the Allied invasion of Italy in 1943.这个故事从1943年盟军入侵意大利开始.
569So if you recall, the Allies had successfully invaded North Africa所以如果你记得,盟军已经成功入侵北非
570and they wanted to get into Europe,他们想进入欧洲,
571so they thought the soft underbelly of Europe所以他们觉得欧洲的软腹
572would be the most effective place to start.这将是最有效的起点。
573And they invaded in September of 1943.并于1943年9月入侵.
574And to their delight, the Italian government意大利政府很高兴
575pretty much immediately surrendered.几乎马上投降了
576And that was great.这是伟大的。
577Except that if they were hoping that the Italian Allies,除了如果他们希望意大利盟军
578the Germans, were going to give up their firm hold on Italy,德军要放弃对意大利的控制
579they were sadly mistaken.可惜他们弄错了
580Despite the loss of their Italian allies,尽管失去了他们的意大利盟友,
581the Germans put up firm resistance.德国人坚挺抵抗
582And by December of 1943,到1943年12月时
583the Germans had established a very strong defensive line德国人建立了非常强大的防线
584just south of Rome, across the width of Italy.就在罗马以南 横跨意大利
585So the Allies were rushing men and supplies into southern Italy所以盟军赶着人和物资进入意大利南部
586to try to keep there and strengthen the first toehold into Europe.试图保持那里,加强第一个进入欧洲的牵制。
587And there's a port called Bari here in southeastern Italy.意大利东南部有个叫巴里的港口
588And they were using this port a great deal.他们经常使用这个港口。
589This anchorage was enclosed by an impressive mile-long jetty.这个锚地被一条长得惊人的防波堤包围着.
590You can see this in the satellite photo.在卫星照片上可以看到这一点。
591And the purpose of this jetty was to serve as a breakwater and pier,这条防波堤的目的是作为防波堤和码头
592but also it reduced the harbor's entrance to a relatively small opening.但也把港口的入口 缩小到一个相对较小的开放点
593And during this time, this harbor was full of Allied ships.在此期间,这个港口充满了盟军船只.
594We're talking of oil tankers,我们在谈论油轮,
595patrol torpedo boats, various smaller crafts.巡逻鱼雷艇 各种小手工业
596These ships were full of ammunition and supplies.这些舰只充满弹药和补给.
597They were so tightly packed that some shipholes touched.他们被紧紧地打包起来 以至于一些船洞被触动了
598And sometimes the port was so busy,有时港口太忙了
599the ships were literally waiting five days to unload their cargoes.船在等五天才卸货
600This is just a wartime photo of part of the harbor side,这只是一张照片 战时部分港口一侧,
601so you can see what it was like.这样你就能看到它是什么样子。
602Now, to speed the unloading of so many ships,现在,为了加速卸载这么多船只,
603the British who were in charge of this area负责这个地区的英国人
604basically suspended the usual blackout orders.基本上暂停了通常的停电命令.
605They believed the Luftwaffe was so severely depleted他们相信德国空军已经消耗殆尽了
606that the odds of an enemy attack were remote.敌人攻击的几率很小
607They neglected to put up much air defense.他们忽略了设置很多防空。
608There was only one anti-aircraft battery that defended the city.当时只有一个防空炮兵保卫城市.
609So they were kind of negligent.所以他们有点失职了
610And they were greatly mistaken about the Luftwaffe.他们误认为是德国空军
611Albert Kesselring was in command of the Nazi troops,阿尔伯特·凯瑟林曾指挥纳粹部队
612the German troops in Italy.在意大利的德国军队
613He realized he had an incredible opportunity here他意识到他有一个不可思议的机会在这里
614and he summoned all available warplanes from across Italy他召集了意大利各地的所有战机
615and northern Italy and ordered them to attack Bari at dusk.和意大利北部,命令他们在黄昏攻击巴里.
616105 bombers heeded the call.105架轰炸机听从了呼叫.
617The attack commenced at 7.25 p.m. and lasted only 20 minutes.攻击于下午7时25分开始,仅持续20分钟。
618Rarely has a fleet of ships ever been caught so unprepared and undefended.很少有一支舰队 被俘虏过如此无备和无防守
619The German bomb set off multiple explosions德国炸弹引发了多起爆炸
620amongst the closely anchored ships laden with fuel and ammunition.与满载燃料和弹药的船舶同船。
621Men leapt from these burning ships into the frigid Adriatic waters.男人从这些燃烧的船跳进冷淡的亚得里亚海中.
622Some were rescued, freezing cold and covered with oil.有的被救出,冷冻,被油覆盖.
623The total number of dead,死者总数
624counting both sailors and civilians, exceeded 1,000.包括水手和平民 超过1000人
625And in all, 17 ships were sunk and eight were badly damaged.而共有17艘船被击沉,8艘严重受损.
626In the army, they started calling this attack the Second Pearl Harbor.在军队中,他们开始称这次攻击为"第二珍珠港".
627And Bari Harbor would be out of action for three months.巴里港三个月后就会停运
628So I love these newsreels because, you know, from the war.所以我喜欢这些新闻片 因为,你知道,从战争。
629And they're so interesting.他们是如此有趣。
630So I have a 60-second newsreel just to give you an idea所以我有一部60秒的新闻片 给你一个想法
631a little bit of what it was like in Bari.有点像在巴里那样
632Sensor clearance now releases these pictures of a damaging raid清除传感器 现在发布这些照片 破坏性突袭
633made by enemy aircraft on the port of Bari on the Italian Adriatic coast.敌机在意大利亚得里亚海岸的巴里港制造
634A low-level night attack which claimed a thousand casualties.一场低级夜间袭击造成1 000人伤亡。
635The heavy death toll was caused by the explosion爆炸造成人员伤亡惨重
636of two ammunition ships hit by German bombs.被德国炸弹击中的两艘弹药船
637In all, 17 allied ships were lost in the disaster.总共有17艘盟军舰艇在灾难中失利.
638Flames spread through the docks in an uncontrolled blaze.火焰在无控制的火焰中通过码头扩散.
639Aviation spirit and high explosives causing one of the worst disasters since Pearl Harbor.航空精神和高爆造成珍珠港以来最严重的灾害之一.
640After the shipping, whose cargo was to supply the 8th Army,运输后, 货物供应第八军,
641was destroyed by two separate blasts from the exploding ammunition ships.被爆炸弹药船的两次爆炸摧毁。
642Some of the vessels remained burning for a week.一些船只被烧了一个星期。
643The disaster precipitated an immediate inquiry这场灾难立即引发了调查
644into the ineffective defenses covering the fall.进入无效的防御 覆盖秋季。
645Okay, great.好吧,伟大的。
646So I hope you like that.所以我希望你喜欢这样
647You know, this was a complete disaster, an unmitigated disaster.你知道,这是一个完全的灾难, 一个没有减轻的灾难。
648And it would really be hard to imagine matters growing even worse for the allies.很难想象盟国会变得更糟
649But believe it or not, they did.但信不信由你,他们做到了。
650In the midst of the attack,在进攻中,
651wounded men and terrified civilians running for cover受伤的男子和惊慌失措的平民
652noticed a peculiar smell in the air.发现空气中有一种怪异的味道
653It smelled like garlic or maybe like mustard.闻起来像大蒜或者芥末
654And it lay heavily across the harbor.它在港口对面沉积着很重
655No one knew what to make of it.没人知道该怎么解释
656And the reason was top secret, okay?原因是绝密的,好吗?
657One American Liberty ship called the John Harvey.美国自由号的一艘飞船叫约翰·哈维号.
658This is a different Liberty ship, a photo of a Liberty ship.这是另一艘自由号飞船 自由号飞船的照片
659It looked like this.看起来像这样
660This is a different ship.这是另一艘船
661But the John Harvey held, believe it or not,但约翰・哈维坚持,相信与否,
662a secret cargo of 2,000 mustard gas bombs, chemical weapons.一种秘密货物 2000芥子气炸弹,化学武器。
663Each weighed about 60 to 70 pounds.每人重约60至70磅.
664An explosion on the John Harvey sent the poison aerosolized into the airJohn Harvey号的爆炸把毒气喷向空气
665and in liquid form spilling into the harbor.以液体形式溢入港口。
666In the water, this toxic fluid was mixed with like viscous oil在水中,这种有毒的液体 像粘性油一样混合
667and coated these sailors who were swimming for their lives并涂上这些水手 他们正在游泳 他们的生命
668in flames and explosions.在火焰和爆炸中,
669And a poisonous cloud kind of wafted over the city of Bari.和有毒的云 一种摇摆在巴里的城市。
670And because the hospitals were inundated with severely injured people,因为医院里挤满了严重受伤的人
671these soldiers who may not have appeared to be as badly hurt at first这些士兵一开始似乎没有那么严重
672were kind of left in their soiled clothing他们的衣物,
673or wrapped in blankets for up to a full day sometimes.或用毯子包起来 有时长达一整天
674If the physicians had known they were coated in toxic fluid,如果医生知道他们涂了有毒液体
675they would have recommended they just shed all their clothes and shower immediately,他们会建议他们立刻脱下所有的衣服和淋浴
676which would have really helped.这会真的有帮助。
677In all, 628 military personnel were hospitalized with mustard poisoning,总共有628名军人因芥子中毒住院
678with symptoms ranging from extensive chemical burns and blisters症状包括广泛的化学烧伤和水泡
679to severe conjunctivitis and temporary blindness.严重结膜炎和暂时失明。
680And within a month, 83 of them would die.在一个月之内,他们中有83人会死。
681So if you're like me, you immediately ask yourself,所以,如果你像我一样, 你立即问自己,
682why did our guys have poison gas?为什么我们的人有毒气?
683Well, you know, the Geneva Convention banned the use of poison gas in war,日内瓦公约禁止在战争中使用毒气
684but not the possession of such gas.但不是拥有这种气体。
685And the American mustard gas had purportedly been brought to Europe美国芥子气据说是带到欧洲的
686as a precaution, just in case the Germans used it first,以防德国人先用它
687so the Allies would have something to retaliate with in kind.所以盟军会用实物报复
688But driven by the fear that disclosure of the facts at Bari但因为害怕泄露巴里的事实
689would prompt a retaliatory German chemical attack,将引发报复性的德国化学攻击,
690the Allies deliberately tried to cover up the mustard gas disaster.盟军故意掩盖芥子气灾难.
691And an army physician named Stuart Alexander was dispatched to Bari一个叫斯图尔特·亚历山大的军医被派往巴里
692to investigate reports of unusual patient symptoms.调查异常病人症状的报告。
693And without knowing about the mustard gas bombs,在不知道芥子气弹的情况下
694his careful investigation deduced that only chemical weapons他仔细调查后推断,只有化学武器
695could explain the constellation of patient findings that he found.可以解释他发现的病人群
696An intact bomb casing with American markings一个有美国标志的完整弹壳
697was retrieved from the bottom of the harbor,从港口底部取回的
698and this had mustard gas in it, confirming his suspicions这里面有芥子气 证实了他的怀疑
699and implicating the Allies.并牵连盟国。
700He noticed, oh, by the way, this is just one page of his top secret report他注意到,哦,顺便说一句, 这只是他的绝密报告的一个页
701back to the army about what he had found in the soldiers回到军队,他发现了士兵
702who had been victimized by the attack.他们成为袭击的受害者。
703He noticed a surprising finding among the patients he was taking care of.他注意到他所照顾的病人中有一个惊人的发现。
704Their white blood cell counts were extremely low.他们的白血球数极低。
705In med school, you learn that a normal white blood cell count在医学院,你学会一个正常的白血球数
706might be 4,500 to 11,000, several thousand per microliter.可能是4,500到11,000,每微利特几千。
707Some of these patients had white blood cell counts less than 100.其中一些病人的白血球数不到100个。
708That is extremely abnormal.这是极其不正常的。
709He deduced correctly that mustard gas had harmed the patient's bone marrow,他正确地推断芥子气伤害了病人的骨髓,
710where infection-fighting white blood cells are produced.与感染作斗争的白血球
711And this made him wonder if this chemical could be investigated这让他怀疑是否该调查这种化学品
712as a potential treatment for cancers related to white blood cell overproduction.作为治疗与白血球过度生产有关的癌症的一种潜在方法。
713He thought to himself, if mustard could do this,他对自己想,如果芥末能做到这一点,
714what could it do for a person with leukemia or lymphosarcoma?它对白血病或淋巴沙科马有什么帮助?
715Whereas mustard gas's effect on bone marrow而芥子气对骨髓的影响
716had largely been ignored during World War I and little studied afterwards,第一次世界大战期间基本上被忽视,之后很少研究,
717now the Bari incident had created and bestowed scientists现在,巴里事件 已经创造和授予科学家
718with a very large case series of human subjects与一个非常大的案件系列 人类主体
719that had been exposed to the toxin and could be carefully studied.并且可以仔细研究。
720Now, back in the U.S., Alexander's work was noticed by Colonel Cornelius Rhodes,现在,回到美国,亚历山大的作品被科内利乌斯·罗兹上校注意到,
721who was the chief of the medical division of the Chemical Warfare Service.曾任化学战局医疗处处长.
722And in 1944, Rhodes organized classified clinical trial of 160 cancer patients1944年,罗兹组织了对160名癌症患者的分类临床试验
723who were treated with nitrogen mustard,他们是被用氮芥子处理的,
724a derivative of the chemical used in mustard gas.芥子气中所使用的化学物质的衍生物。
725This study showed positive results in patients with lymphoma.这项研究显示,淋巴瘤患者有积极的结果。
726And in 1949, the first cancer chemotherapy medication to be approved by the FDA在1949年,第一个癌症化疗药物 由FDA批准
727was a form of nitrogen mustard called misstargon.是氮芥的一种叫迷信塔贡
728It would be the vanguard of a new class of chemotherapy drugs它将成为新一类化疗药物的先锋
729called alkylating agents that are still used today.叫做烷基化剂,今天仍在使用
730So thanks largely to the catastrophic disaster at Bari,多亏了巴里的灾难性灾难
731a new method of combating cancer had been launched.已经推出了一种防治癌症的新方法。
732Remember, prior to this, cancer could only be treated by surgery记住,在这之前 癌症只能通过手术治疗
733to remove a local tumor or sometimes radiation.以去除局部肿瘤或有时辐射。
734There was no way of treating, you know, blood cancers or metastases.没有办法治疗血液癌或元病
735Now chemotherapy offered a chance to kill cancer wherever it lived.现在化疗提供了一个杀死癌症的机会 无论它住在哪里。
736And despite major advances in oncology today, even immunotherapy,尽管肿瘤学取得了重大进步 即使是免疫疗法
737which is the hot topic of the day,这是今天的热门话题,
738chemotherapy is still the mainstay of treatments for most major cancers in patients.化疗仍然是治疗患者大多数主要癌症的支柱。
739So this is the first chemotherapy that we got,所以这是我们第一次接受化疗
740and it's because of Bari and the Luftwaffe bombing raid there.是因为巴里和德国空军的轰炸
741It's just an incredible story.这只是一个不可思议的故事。
742You know, medical history is full of these stories.医学史上都是这些故事
743These two stories I've shared with you tonight,今晚我和你们分享的两个故事
744they occupy each only four pages of my book.他们只占有我书的四页
745There are so many stories that have changed all our lives.有很多故事改变了我们的生活
746So just to sum up briefly,所以简单总结一下,
747what lessons can we learn from these stories of discovery in World War II?我们能从二战的这些发现故事中吸取什么教训?
748First, necessity is the mother of invention.第一,必要性是发明之母。
749Without World War II, Dwight Harkin would never have been confronted没有二战,德怀特·哈金就永远不会面对
750with the heart wounds that allowed him to experiment心脏受伤 使他得以实验
751and launch the field of cardiac surgery.并启动心脏手术领域。
752Second, it takes maverick doctors like Charles Bailey to take chances第二 查尔斯·贝利这样的医生要冒险
753and sometimes risk their reputations and careers有时还冒着名誉和事业的风险
754to make a breakthrough that everyone else thinks is impossible or crazy.实现别人认为不可能或疯狂的突破
755And finally, we see that when humanity is at its worst最后,我们看到当人类处于最糟糕的状态时
756in the midst of such catastrophic disasters like World Wars,在诸如世界大战等灾难性灾难中,
757there are still extraordinary examples of human compassion and diligence人类的同情和勤奋 仍然有非凡的例子
758exemplified by doctors like Stuart Alexander,以斯图尔特·亚历山大等医生为例,
759who was able to think outside the box and recognize a new observation他能从盒子外思考 并意识到新的观察
760like low white blood cell count in much of the gas victims像低白血球数 在大部分毒气受害者
761and apply it to follow like no one else had ever dreamed of doing before.并把它应用到跟以前没有人梦想的那样。
762The only winner in war is medicine.战争中唯一的胜利者是医学.
763And thank goodness we can be thankful and grateful谢天谢地 我们可以感激和感激
764that even in our darkest hours, there are those among us即使在我们最黑暗的时光里 我们中也有人
765who rise to the occasion and can inspire each of us to do他们能激励我们每个人
766what is altruistic and honorable and the best in whatever community什么是利他主义,什么是荣誉 和最好的在任何社区
767and circumstance we find ourselves in.以及我们所处的环境
768Thank you so much for spending some of your evening with me tonight.谢谢你今晚陪我过夜
769I love sharing my passion for history and medicine我喜欢分享我对历史和医学的热情
770and I hope you learned something you didn't already know before.我希望你学到一些你以前不知道的东西
771Well, Andrew, thank you so much for giving this riveting presentation安德鲁 非常感谢你做了这个精彩的演讲
772and sharing these very inspiring stories.并分享这些非常鼓舞人心的故事。
773I totally agree with you that, you know,我完全同意你的观点,你知道,
774there are a lot of these sorts of untold stories有很多这种难以形容的故事
775that deserve to be celebrated along with, you know,值得庆祝的是,你知道,
776many interesting people that we now know who are commanding our attention.许多有趣的人,我们现在知道谁值得我们注意。
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